Syntacks Active

SYN®-TACKS organizes your Dermal-Epidermal
Junction (DEJ) to reach the “top of beauty”.

Helping skin to behave in a healthy way is the major target of cosmetic research. However, traditional approaches to skin aging appear today to be incomplete, particularly considering changes occurring at the dermal–epidermal junction (DEJ) and the evaluation of the changes of key proteins therein. The functionality of the DEJ that provides structural and functional integrity to the skin starts to change at around the age of 30. This process goes along, and is even accelerated by external influences such as UV light, with decreasing skin compactness, elasticity and a lack of skin firmness.

Properties:
SYN®-TACKS, the combination of two peptides offers for the first time the possibility to interact with the most relevant protein structures of the dermal-epidermal junction (DEJ). SYN®-TACKS significantly stimulates Laminin V, Collagen type IV, VII and XVII and Integrin at once. Only by this broad spectrum activity it is guaranteed to achieve the utmost structural benefit for the skin. By increasing the activity of these proteins the whole structure of the DEJ is improved. This finally leads to a visible cosmetic benefit.

Function of SYN®-TACKS:
• improved structural integrity
• improved epidermal nourishment
• improved molecular communication within the skin

this leads to:
• improved skin compactness
• reduced wrinkles
• increased skin tonicity
• increased skin firmness

Cosmetic application:
• Skin compactness and skin restructuring treatments
• Anti aging cure and anti wrinkle products
• Skin protecting elixir and sun-care lines
• Barrier function and skin repair treatments

Suggested concentration:
For skin care preparations, we recommend the addition of 1% SYN®-TACKS.

INCI name:
Glycerin, Palmitoyl Dipeptide-5 Diaminobutyloyl Hydroxythreonine, Palmitoyl Dipeptide-6 Diaminohydroxybutyrate

Efficacy tests:
In vitro tests:
Stimulation of the relevant DEJ proteins by Palm-Lys-Val-Dab-Thr (50 μM, in red) and Palm-Lys-Val-Dab (100 μM, in orange).

Summary of clinical investigation
• SYN®-TACKS improves after only two months skin tonicity by 32%.
• SYN®-TACKS improves skin anisotropy up to 62%.
• SYN®-TACKS improves cellular cohesion up to 23%.
• Scanning electron microscopy shows a significant skin benefit.
• Macro photographs show the benefit of using SYN®-TACKS.
• SYN®-TACKS got excellent ratings in the evaluation questionnaire, 87% would purchase the product again.

SYN®-tacks is a registered trademark of Pentapharm.