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5 Reasons to Micro-Needle with EXO-PDRN
Micro-needling creates the pathway. EXO-PDRN delivers what your skin actually needs to rebuild—marine DNA, dual DNA repair enzymes, and repair peptides that trigger lasting regeneration.
#1: Trigger Real Collagen Production
Most serums sit on the surface. Even powerful ingredients can't reach your fibroblasts—the cells that actually make collagen and elastin. Micro-needling changes that.
At 562,400 PPM, PDRN activates adenosine A2A receptors on fibroblasts, triggering increased production of Vascular Endothelial Growth Factor (VEGF) and enhanced collagen synthesis.[1] You're not just plumping temporarily—you're rebuilding your skin's structure from within.
#2: Fix the DNA Damage That's Aging You
Every day, UV exposure and pollution damage your skin's DNA. Most of that damage never gets repaired—it justEvery day, UV exposure and pollution damage your skin's DNA. Most of that damage never gets repaired—it just accumulates, causing wrinkles, dark spots, and loss of function over time.
EXO-PDRN is the only PDRN serum with dual DNA repair enzymes. Endonuclease (Micrococcus Lysate) recognizes and removes UV-induced bulky lesions by cutting damaged DNA sections, while Glycosylase OGG1 (Arabidopsis Thaliana Extract) specifically removes oxidized bases like 8-oxoguanine caused by pollution and environmental stress. Unlike photolyase enzymes that need light activation, these work 24/7.
You're not just building new skin—you're ensuring the blueprint for that new skin is correct. accumulates, causing wrinkles, dark spots, and loss of function over time.
#3: Better Results Than PRP
Your skin is always red, reactive, or inflamed. Post-treatment recovery takes forever. Your barrier is compromised, and inflammation keeps aging your skin faster.
A 2025 randomized controlled trial compared micro-needling with PDRN versus micro-needling with Platelet-Rich Plasma (PRP) for wrinkles and hyperpigmentation. Both treatments worked—but PDRN showed significantly greater wrinkle reduction (p=0.021).[3]
The study involved 24 women aged 30-50 receiving two treatments three weeks apart. While PRP has its benefits, PDRN's unique ability to activate adenosine receptors gives it an edge in collagen stimulation and tissue repair.
#4: Recover Faster Between Treatments
Redness and inflammation after micro-needling can last for days. That downtime makes it harder to stay consistent with treatments—and consistency is what delivers results.
PDRN has been clinically proven to reduce inflammation and accelerate tissue oxygenation. In a study on wound healing, PDRN-treated patients showed significant improvements in tissue oxygenation at days 7, 14, and 28 (p<0.001), with increased angiogenesis and improved inflammation markers.[4]
Add Beta-Glucan for immediate calming and Copper Tripeptide-1 to organize the repair process, and most customers wake up the next day with calm, hydrated skin instead of prolonged redness.
Faster recovery = more frequent treatments = better cumulative results.
#5: Smooth Texture and Remodel Scars
Acne scars, surgical scars, uneven texture—they're all caused by disorganized collagen deposition. Your skin healed, but it didn't heal evenly.
A 2023 randomized controlled trial on scar prevention showed PDRN significantly reduced scar vascularity (p=0.010), erythema, and scar height compared to untreated controls.[5] PDRN promotes organized tissue regeneration while Copper Tripeptide-1 ensures new collagen is laid down smoothly.
When you micro-needle with EXO-PDRN, you're creating the right environment for proper remodeling—scars flatten, texture evens out, and new collagen forms correctly from the start.
The Bottom Line
Most serums either stimulate new growth OR protect against damage. EXO-PDRN does both:
- Marine DNA (562,400 PPM) that activates fibroblasts and triggers collagen production
- DNA repair enzymes that fix UV and oxidative damage at the cellular level
- Proven faster recovery and reduced inflammation
- Better wrinkle reduction than PRP in clinical studies
- Organized healing for smoother texture and scar remodeling
-
Injection-grade purity formulated specifically for deep delivery
It's not just about making micro-channels—it's about what you send through them.
Quick wins - why customers love it
“I've been using Vitamin C serum for about one month and I love how it makes my skin feel. “"My skin looked and felt wonderful the next day!" "This PDRN serum is soothing and felt so calming. My skin looked and felt wonderful the next day! I will definitely continue using EXO-PDRN for both microneedling and as part of my skincare routine."
Donna H., Roanoke, VA
"My skin is glowing!" "Love the results. My skin is glowing after using these ampules after microneedling. Will order again."
Susan F., Durango, CO
"So much better than using HA" "The Exo-PDRN made my skin so glowy! I used it instead of HA while microneedling. It was so much better than using HA then applying a serum with actives."
Nicole P., Minneapolis, MN
"My husband has even noticed" "I have mature, dry and sensitive skin. Whether using PDRN added to EXO for micro infusion or on its own—my skin soaks this stuff right up. Irritation, dryness gone. My skin looks so much better with PDRN in my routine. My husband has even noticed."
Kimberly P., Oklahoma City, OK
What to Expect
Your EXO-PDRN Journey
PDRN activates cellular repair. DNA enzymes begin fixing damage. Beta-Glucan soothes immediately. You'll notice: reduced redness, deep hydration, plumper texture—especially noticeable post-treatment.
Fibroblast activity increases. Collagen production ramps up. DNA damage correction accelerates cellular function. You'll notice: smoother texture, enhanced radiance, improved "bounce," reduced appearance of fine lines.
New collagen matures. Skin architecture rebuilds. DNA continues being repaired faster than it accumulates. You'll notice: significant improvement in firmness, wrinkles soften, scars flatten, skin tone evens out, thicker, more resilient skin. .
Cumulative cellular repair creates lasting change. Skin maintains better hydration and resilience. DNA damage is continuously corrected. You'll notice: dramatic improvement in overall skin quality, deep wrinkles show significant improvement, skin appears years younger, better protection from environmental damage.
Bottom Line: Results compound with consistent use. For maximum impact, combine micro-needling treatments (every 2-4 weeks) with daily topical use between sessions.
The Story Behind EXO-PDRN
Discover why we created a marine DNA serum with breakthrough DNA repair enzymes—and how this complete cellular system delivers results other regenerative serums can't match.
Powered by Marine Science + DNA Repair Technology
Each ingredient is chosen for its proven ability to repair, regenerate, and protect at the cellular level.
Why EXO-PDRN
Stands Apart
Feature | EXO-PDRN | Standard PDRN Serums | HA-Only Serums |
PDRN Concentration | 562,400 PPM (Injection-Grade) | Often <100,000 PPM or undisclosed | None |
DNA Repair Enzymes | Dual (UV + Oxidative) | ||
Repair Peptides | Copper Tripeptide-1 | Sometimes | |
Barrier Support | Beta-Glucan | Rarely | Sometimes |
Complete System | Regeneration + DNA Repair | Regeneration Only | Hydration Only |
Purity Level | Injection-Grade | External use grade typical | N/A |
Clinical Backing | 600+ Studies | Varies | Moderate |
Micro-Needling Optimized | Sometimes | ||
Preservative-Free Option | Varies | Usually | |
Why EXO-PDRN Wins | EXO-PDRN | Other PDRN Serums |
Complete DNA Repair System (Dual Enzymes) | ||
562,400 PPM (Injection-Grade) | MOST | |
Repair Peptides + Barrier Suppor | ||
Regeneration + DNA Protection | ||
600+ Clinical Studies | ||
Micro-Needling Optimized | SOMETIMES | |
| Treatment | Details | Cost | Cost Per Treatment |
|---|---|---|---|
| EXO-PDRN | 15ml total (3 x 5ml bottles) | $70 | $23.33 (when used with micro-needling at home) |
| Professional PDRN Treatment | Professional PDRN Treatment | $300-500 | $300-500 |
| Treatment | Details |
|---|---|
| EXO-PDRN | 15ml total (3 x 5ml bottles) |
| Professional PDRN Treatment | Professional PDRN Treatment |
| Cost | Cost Per Treatment |
|---|---|
| $70 | $23.33 (when used with micro-needling at home) |
| $300-500 | $300-500 |
How to Use EXO-PDRN for Maximum Results
For Alqemi Micro-Infusion or Micro-Needling:
Step 1: Prepare Cleanse skin thoroughly. Ensure skin is completely dry. Set up your Alqemi tool according to instructions.
Step 2: Fill Tool Fill reservoir with EXO-PDRN. Can mix with EXO-AD, EXO-SPOT, or EXO-EHR for multi-concern treatments. Mix fresh for each session.
Step 3: Perform Treatment Follow device protocol for infusion pattern and depth. The micro-channels allow deep penetration to maximize cellular repair.
Step 4: Apply Remaining Serum Open tool and apply remaining serum to face, neck, and chest. Pat gently until absorbed.
Frequency: Every 2-4 weeks
For Daily Topical Use
Mix Into Your Products: Add EXO-PDRN to your favorite serum or moisturizer with preservatives (like Regenerate, Nano Hyaluronic, or Dr. Platinum Potions). This extends shelf life and gives you ongoing regenerative benefits.
Storage After Mixing:
- Room temperature: Use within 2 months
- Refrigerated: Use within 3 months
- *Mandatory refrigeration if combined with EXO-AD Exosomes
Application: Mix your custom blend in palm before applying, or layer as your first serum followed by moisturizer and SPF 50+.
When: Morning or evening (or both)
Why Mix Instead of Using Alone? Since EXO-PDRN is preservative-free, opened bottles must be used within 48 hours. Mixing into preserved products lets you enjoy the benefits long-term without waste.
Pro Tips
💡 Always use SPF 50+ after treatment—skin will be more UV-sensitive
💡 Don't waste leftover serum from micro-needling—apply to face, neck, chest, hands, or any area with aging concerns
💡 Mix for custom treatments: Combine with EXO-SPOT (brightening), EXO-AD (exosomes), or EXO-EHR (peptides)
💡 Never combine micro-needling with chemical peels in the same session
💡 Wait 2-4 weeks between micro-needling treatments
Why Platinum?
Who we are
Skincare experts with decades of experience, we’re passionate about helping you achieve your best skin yet with professional-grade products trusted by clinics and skincare enthusiasts alike.
Our Mission
Empowering your skin transformation by bringing professional-quality skincare into your home with products and guidance that put you in control of your results.
Our Promise to You
Your skin’s safety is our priority. Every product is pH-calibrated, thoroughly tested, and backed by detailed instructions, so you can peel with confidence.
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Try EXO-PDRN Risk-Free
We're confident EXO-PDRN will transform your skin. Try it for 30 days. If you're not completely satisfied, return it for a refund (minus 15% restocking fee) or 100% store credit.
Our Quality Promise:
- Injection-grade PDRN backed by 600+ clinical studies
- DNA repair enzymes with proven efficacy
- Manufactured to the highest standards
- No unnecessary fillers or irritants
- Cruelty-free and sustainably sourced
Need Help?
Need Help? Our skincare experts are available to answer questions about EXO-PDRN and how it fits into your routine.
FAQ
How long does one bottle last?
Each 5ml bottle is designed for one micro-needling treatment (with some leftover to apply topically or mix into daily products).
Package of 3 bottles:
- Micro-needling only: 3 treatments (one every 2-4 weeks = 6-12 weeks of treatments)
- Micro-needling + daily boost: 3 treatments plus mix remaining serum into your daily products for ongoing benefits between treatments
- Daily use only: Mix into preserved serums (like Regenerate) - can last several months depending on how much you mix in
Best value approach: Use one bottle per micro-needling treatment, then mix any remaining serum into your daily routine until your next treatment.
When will I see results?
Immediate (24-48 hours): Calming, hydration, reduced redness 1 week: Improved texture and radiance 4-8 weeks: Visible firmness, fine line reduction, scar improvement 3-6 months: Dramatic transformation in skin quality
Results compound with consistent use. Combine micro-needling (every 2-4 weeks) with daily application for best results.
Can I use this with retinol or acids?
Yes, but timing matters:
- If using daily: Apply EXO-PDRN first, wait 5 minutes, then apply retinol or acids
- Post-micro-needling: Wait 24-48 hours before resuming retinol or acids
- During recovery: EXO-PDRN is perfect for use after peels or laser treatments
Is this safe for sensitive skin?
Yes. EXO-PDRN is injection-grade quality, non-irritating, and non-sensitizing. Beta-Glucan provides immediate soothing. Perfect for sensitive skin and post-treatment recovery.
Can I mix EXO-PDRN with other Alqemi products?
Absolutely! Mix with:
- EXO-AD for added exosome power
- EXO-SPOT to target both aging and pigmentation
- EXO-EHR for additional growth factors and peptides
For daily use, mix into Regenerate, Nano Hyaluronic, or Dr. Platinum Potions to extend shelf life.
What is PDRN and why 562,400 PPM matters?
PDRN (Polydeoxyribonucleotide) is salmon-derived DNA that activates cellular repair mechanisms. The concentration matters—most PDRN products contain less than 100,000 PPM or don't disclose concentration at all. At 562,400 PPM, EXO-PDRN delivers therapeutic levels proven effective in clinical studies.
What makes the DNA repair enzymes special?
These are the same breakthrough enzymes found in EXO-SPOT:
- Endonuclease (Micrococcus Lysate) removes UV-induced bulky lesions that cause photoaging
- Glycosylase OGG1 (Arabidopsis Thaliana Extract) repairs oxidative damage from pollution and environmental stress
Unlike photolyase enzymes that require light activation, both of these work continuously 24/7 to repair accumulated DNA damag
Is this the same DNA repair technology as EXO-SPOT?
Yes, both contain the same dual DNA repair enzymes. The difference:
- EXO-PDRN: DNA Repair + Regeneration (aging, elasticity, healing focus)
- EXO-SPOT: DNA Repair + Brightening (pigmentation focus)
They work beautifully together for comprehensive treatments.
How should I store EXO-PDRN?
Unopened: Store at room temperature, 2-year shelf life
For micro-needling: Use opened bottle within 48 hours OR mix into a serum with preservatives. Do not refrigerate.
For daily use: Mix with a preserved serum (like Regenerate). Lasts 2 months at room temperature, 3 months refrigerated.
If mixed with EXO-AD: Refrigeration is mandatory.
Is this safe during pregnancy or breastfeeding?
While PDRN is generally considered safe, we always recommend consulting your healthcare provider before starting new skincare products during pregnancy or breastfeeding.
Can this help with acne scars?
Yes. PDRN is clinically proven to improve both raised and atrophic scars by promoting organized tissue regeneration. For best results, use with micro-needling and be consistent—scars require several treatments to see significant improvement
Why doesn't it contain preservatives?
We formulated without preservatives for maximum ingredient efficacy and to minimize irritation on freshly micro-needled skin. The trade-off requires proper handling (use within 48 hours or mix with preserved products), but delivers pure, powerful ingredients at peak effectiveness.
Can I use this without micro-needling?
Yes! Mix EXO-PDRN into your daily serums or moisturizers for ongoing regenerative benefits. Since it's preservative-free, mixing with preserved products (like Regenerate, Nano Hyaluronic, or Dr. Platinum Potions) extends shelf life to 2-3 months. You'll still get significant cellular repair benefits from daily use—micro-needling just enhances penetration for even more dramatic results.
How does this compare to professional PDRN treatments?
Professional PDRN injections ($300-500 per session) deliver PDRN directly into the dermis. EXO-PDRN delivers injection-grade PDRN topically—enhanced by micro-needling for deeper penetration. You get professional-quality results with more control, at a fraction of the cost, plus the added benefit of DNA repair enzymes not included in professional treatments.
What skin concerns can EXO-PDRN address?
- Fine lines and wrinkles
- Loss of firmness and elasticity
- Acne scars and surgical scars
- Uneven texture
- Hyperpigmentation (especially when combined with EXO-SPOT)
- Post-treatment recovery (peels, lasers, micro-needling)
- Compromised skin barrier
- Chronicinflammation and redness
- Dehydration
